Case Comprehensive Cancer Center
Case Western Reserve University
Cleveland, OH
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MDS Centers of Excellence
Accepting patients
Azacitidine and Decitabine
Proof-Of-Concept Study of Metabolically Optimized, Non-Cytotoxic 5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
Learn more- Hypomethylating Agents (HMA)
- Phase 1
Not yet accepting
Donor Lymphocyte Infusion Post-Transplant
Preemptive Infusion of Donor Lymphocytes Depleted of TCR (Alpha-beta) + T Cells and CD19+ B Cells Following Allogeneic Stem Cell Transplantation
Learn more- Donor Lymphocyte Infusion (DLI)
- Phase 1
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Connect® Myeloid: The Myelofibrosis (MF), Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry
Learn more- Observational Trial
Accepting patients
Ivosidenib (AG120)
Phase Ib/II Investigator Initiated Study of the IDH1-Mutant Inhibitor Ivosidenib (AG120) With the BCL2 Inhibitor Venetoclax +/- Azacitidine in IDH1-Mutated Hematologic Malignancies
Learn more- BCL-2 Inhibitor
- Hypomethylating Agents (HMA)
- IDH1 Inhibitor
- Phase 1/2
- Has results
Accepting patients
NK Cells Plus Vactosertib
A Phase Ib Study to Evaluate Safety and Persistence of ex Vivo Expanded Universal Donor NK Cells in Combination With IL-2 and TGFbeta Receptor I Inhibitor Vactosertib in Patients With Locally Advanced/Metastatic Colorectal Cancer and Relapsed/Refractory Hematologic Malignancies
Learn more- Kinase Inhibitor
- Natural Killer Cells (Allogeneic)
- Phase 1