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Accepting patients

Olutasidenib

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.
  • IDH1 Inhibitor
  • Phase 2

Accepting patients

Cord Blood Transplant

Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults
  • Cord Blood
  • Phase 2

Accepting patients

Cord Blood Transplantation in Children

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

Optimized Cord Blood Transplant

Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults and Pediatrics
  • Cord Blood
  • Phase 2

Accepting patients

ELRiSE MDS

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions (ELRiSE MDS)
  • Activin Receptor IIA Inhibitor
  • Randomization
  • Phase 3

Accepting patients

IRAK

Phase 1b Study of R289 in Patients with Lower-risk Myelodysplastic Syndromes (LR MDS)
  • IRAK 1 Inhibitor
  • IRAK 4 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

RENEW

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
  • Activin Receptor IIA Inhibitor
  • Placebo
  • Closed Label (Masked)
  • Phase 3

Accepting patients

GLB-001

A First-in-human, Phase 1, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
  • Cyclin-Dependent Kinase Inhibitor (CDK Inhibitor)
  • High Risk
  • Phase 1

Accepting patients

BH-30236

A Phase 1/1b Open-Label, Dose Escalation, First-in- Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-leukemic Activity of the Orally Available CDC-Like Kinase (CLK) Inhibitor, BH-30236, in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML) or Higher-Risk Myelodysplastic Syndrome (HR-MDS)
  • CLK Inhibitor
  • Phase 1

Accepting patients

REM-422

A Phase 1, Multicenter, Open-Label Study of REM-422, an MYB mRNA Degrader, in Patients With Relapsed/Refractory AML or Higher-Risk MDS
  • MYB mRNA Degrader
  • Phase 1