National Institutes of Health
Bethesda, MD
Accepting patients
Pacritinib
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms
- Kinase Inhibitor
- Phase 1/2
Accepting patients
Collection of Tissue Samples for Cancer Research
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)
- Observational Trial
Accepting patients
Autologous T Cells
A Phase I Study of Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Other Hematologic Malignancies
- T Cell
- Phase 1
Accepting patients
Donor Lymphocyte Infusion Post Transplant
Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies
- Donor Lymphocyte Infusion (DLI)
- Post-Allogeneic Stem Cell Transplant
- Phase 1/2
Accepting patients
Collection of Biological Samples
Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS
- Observational Trial
Accepting patients
Allo Stem Cell Transplant for GATA2 Mutations
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Mutations in GATA2 or the MonoMAC Syndrome
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
G-CSF Mobilized CD34+ Cells in Transplant
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells
- Allogeneic Stem Cell Transplant
- CD34
- Phase 2
Accepting patients
Safety Study of Cord Blood Units
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Natural History Study
The Natural History of Acquired and Inherited Bone Marrow Failure Syndromes.
- Observational Trial
Accepting patients
Post-Transplant Cyclophosphamide
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis
- Allogeneic Stem Cell Transplant
- Chemotherapy
- Post-Allogeneic Stem Cell Transplant
- Phase 2