National Institutes of Health (Bethesda)
Bethesda, MD
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MDS Centers of Excellence
Accepting patients
Collection of Biological Samples
Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS
Learn more- Observational Trial
Accepting patients
Omidubicel (former CordIn)
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, to Expedite Engraftment and Improve Transplant Outcome
Learn more- Cord Blood
- Phase 1/2
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G-CSF Mobilized CD34+ Cells in Transplant
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells
Learn more- Allogeneic Stem Cell Transplant
- CD34
- Phase 2
Accepting patients
Safety Study of Cord Blood Units
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients
Learn more- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Post-Transplant Cyclophosphamide
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis
Learn more- Allogeneic Stem Cell Transplant
- Chemotherapy
- Phase 2
Accepting patients
GATA2 Genetic Testing
The Natural History of GATA2 Deficiency and Related Disorders
Learn more- Genetic Sequencing
- Observational Trial
Accepting patients
Collection of Tissue Samples for Cancer Research
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)
Learn more- Observational Trial
Accepting patients
Natural History Study
The Natural History of Acquired and Inherited Bone Marrow Failure Syndromes.
Learn more- Observational Trial
Accepting patients
Allo Stem Cell Transplant for GATA2 Mutations
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Mutations in GATA2 or the MonoMAC Syndrome
Learn more- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Eltanexor Plus Inqovi
A Phase I/II Trial of Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes
Learn more- Nucleoside Metabolic Inhibitor
- SINE
- Phase 1/2