Mayo Clinic (Rochester)

Accepting patients

Mismatched Related vs. Matched Unrelated Donor

A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) Versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) With Acute Leukemia or Myelodysplastic Syndrome (MDS)
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  • Allogeneic Stem Cell Transplant
  • Monoclonal Antibody
  • Phase 3

Accepting patients

PRGN-3006 Adoptive Cellular Therapy

A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome
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  • CAR T Cell
  • CD33
  • Phase 1
  • Has results
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Accepting patients

ACCESS

ACCESS: A Multicenter, Phase II Trial of HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide for Patients with Hematologic Malignancies
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  • Allogeneic Stem Cell Transplant
  • Pre-Transplant
  • Phase 2

Not yet accepting

Phase 1/2 Multicenter, Open-Label Study of CTX-712 in Patients With Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes
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  • CLK Inhibitor
  • Phase 1/2

Accepting patients

DFV890

A Phase 1b, Open Label, Multi-center, Dose Optimization and Dose Expansion Study to Assess the Safety and Efficacy of DFV890 in Adult Patients With Myeloid Diseases
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  • NLRP3 Inhibitor
  • Phase 1

Accepting patients

PedAL Screening

Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias
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  • Phase 1/2

Accepting patients

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study
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  • Observational Trial

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