Memorial Sloan Kettering Cancer Center

Accepting patients

Cord Blood Transplant

Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults
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  • Cord Blood
  • Phase 2

Accepting patients

Condensed Busulfan, Melphalan, and Fludarabine

A Pilot Study of Condensed Busulfan, Melphalan, and Fludarabine Conditioning prior to ex vivo CD34+ Selected Allogeneic Hematopoietic Cell Transplantation
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  • Allogeneic Stem Cell Transplant
  • Phase 1
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Accepting patients

BTX-A51

A First-In-Human, Open-Label, Escalating Multiple-Dose Study to Evaluate the Safety, Toxicity, and Pharmacokinetics of BTX-A51 Capsules Alone and in Combination With Azacitidine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
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  • Cyclin-Dependent Kinase Inhibitor
  • Kinase Inhibitor
  • Phase 1
  • Has results

Accepting patients

Cord Blood Transplantation in Children and Young Adults With Hematologic Malignancies and Non-malignant Disorders
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  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

OPTIMIZE

A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHD Prophylaxis in Adult Patients With Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
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  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

Smart Immune

A Phase I/II Study Evaluating the Safety and the Efficacy of SMART101 Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution after T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric and Adult Patients with Acute Leukemia
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  • Phase 1/2

Accepting patients

GLB-100

A First-in-human, Phase 1, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
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  • High Risk
  • Phase 1

Accepting patients

FHD-286

A Phase 1, Multicenter, Open-Label, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered FHD-286, as Monotherapy or Combination Therapy, in Subjects With Advanced Hematologic Malignancies
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  • BRG1 Inhibitor
  • BRM Inhibitor
  • Phase 1
  • Has results

Accepting patients

REM-422

A Phase 1, Multicenter, Open-Label Study of REM-422, an MYB mRNA Degrader, in Patients With Relapsed/Refractory AML or Higher-Risk MDS
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  • MYB mRNA Degrader
  • Phase 1

Accepting patients

Antibiotics During Stem Cell Transplant

IIT: Rational Use of Broad-spectrum Antibiotics as Empiric Antibiotic Therapy in Febrile Neutropenia in Recipients of Allogeneic Hematopoietic Cell Transplantation
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  • Chemotherapy
  • Phase 2

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