Memorial Sloan Kettering Cancer Center
New York, NY
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Orca-T
A Randomized Phase III Trial of Patients With Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation With Either Orca-T, a T-cell-Depleted Graft With Additional Infusion of Conventional T Cells and Regulatory T Cells, or Standard-of-Care Allogeneic Graft
Learn more- Allogeneic Stem Cell Transplant
- T Cell (Allogeneic)
- Phase 3
- Has results
Accepting patients
Condensed Busulfan, Melphalan, and Fludarabine
A Pilot Study of Condensed Busulfan, Melphalan, and Fludarabine Conditioning prior to ex vivo CD34+ Selected Allogeneic Hematopoietic Cell Transplantation
Learn more- Allogeneic Stem Cell Transplant
- Phase 1
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BTX-A51
A First-In-Human, Open-Label, Escalating Multiple-Dose Study to Evaluate the Safety, Toxicity, and Pharmacokinetics of BTX-A51 Capsules Alone and in Combination With Azacitidine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Learn more- Cyclin-Dependent Kinase Inhibitor
- Kinase Inhibitor
- Phase 1
- Has results
Accepting patients
Orca-T
A Multicenter Phase Ib Trial of Patients With Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation With Orca-T (Formerly TregGraft), a T-cell-Depleted Graft With Additional Infusion of Conventional T Cells and Regulatory T Cells
Learn more- T Cell (Allogeneic)
- Phase 1
- Has results
Accepting patients
Cord Blood Transplantation in Children and Young Adults With Hematologic Malignancies and Non-malignant Disorders
Learn more- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
OPTIMIZE
A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHD Prophylaxis in Adult Patients With Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
Learn more- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Smart Immune
A Phase I/II Study Evaluating the Safety and the Efficacy of SMART101 Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution after T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric and Adult Patients with Acute Leukemia
Learn more- Phase 1/2
Accepting patients
GLB-100
A First-in-human, Phase 1, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
Learn more- High Risk
- Phase 1
Accepting patients
FHD-286
A Phase 1, Multicenter, Open-Label, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered FHD-286, as Monotherapy or Combination Therapy, in Subjects With Advanced Hematologic Malignancies
Learn more- BRG1 Inhibitor
- BRM Inhibitor
- Phase 1
- Has results
Accepting patients
REM-422
A Phase 1, Multicenter, Open-Label Study of REM-422, an MYB mRNA Degrader, in Patients With Relapsed/Refractory AML or Higher-Risk MDS
Learn more- MYB mRNA Degrader
- Phase 1
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