Decitabine/Cedazuridine as Maintenance Therapy

A Phase Ib Study of Oral Decitabine/Cedazuridine as Maintenance Therapy Following Allogeneic Hematopoietic Cell Transplantation for Patients With Myeloid Neoplasms

What's the purpose of the trial?

This research is being done to see if the drug Inqov is effective in reducing the chance of myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) relapsing after standard of care stem cell transplant. * This research study involves the study drug Inqovi, which is a combination of the drugs decitabine and cedazuridine.
Trial status

Accepting patients

Phase
Phase 1
Enrollment
22
Last Updated
2 days ago
Am I Eligible

Participating Centers

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Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • Inqovi is an oral chemotherapy medication. It combines two different drugs, decitabine, which is a hypomethylating chemotherapy agent, and cedazuridine, which is a CDA inhibitor that helps decitabine to work effectively in the body.

Arms / Cohorts

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Accepting patients

Dose Escalation: Inqovi

Accepting patients

Recommended Phase 2 Dose Expansion: Inqovi

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