Donor Lymphocyte Infusion Post-Transplant
Preemptive Infusion of Donor Lymphocytes Depleted of TCR (Alpha-beta) + T Cells and CD19+ B Cells Following Allogeneic Stem Cell Transplantation
What's the purpose of the trial?
The purpose of this study is to reduce the risk of cancer relapse by giving a donor lymphocyte infusion (DLI) to boost the immune system early after a stem cell transplant so that leukemia cells that escaped chemotherapy can be detected and killed. This DLI will contain mostly lymphocytes that have graft versus tumor effect with low risk of graft versus host disease. Because the process of giving a DLI in the first four weeks after a transplant has not been approved by the Food and Drug Administration (FDA), this study in investigational (experimental).
Trial status
Not yet accepting
Phase
Phase 1
Enrollment
10
Last Updated
1 week ago
Participating Centers
There is one center participating in this trial. Enter a location below to view the distance.
Experimental Treatments
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- Donor Lymphocyte Infusion (DLI) is an infusion of lymphocytes (usually T cells) that come from a donor.
Arms / Cohorts
Explore eligibility, treatments and learn more about potential cohorts.
Not yet accepting
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