SL-172154
An Open-Label Phase 1a/1b Dose Escalation and Expansion Cohort Study of SL-172154 (SIRPα-Fc-CD40L) in Combination With Azacitidine or With Azacitidine and Venetoclax for the Treatment of Subjects With Higher-Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
Arms / Cohorts
Experimental:SL-172154
Accepting patients
Experimental:Untreated MDS Patients: SL-172154 + Azacitidine (Dose Escalation)
Accepting patients
Experimental:R/R MDS Patients: SL-172154 + Azacitidine (Dose Escalation)
Accepting patients
Experimental:Untreated MDS Patients: SL-172154 + Azacitidine (Dose Expansion)
Accepting patients
Experimental:SL-172154 + Azacitidine + Venetoclax
Accepting patients
Experimental, Part D:Untreated High-Risk MDS Patients: SL-172154
Accepting patients
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