Vorinostat for GVHD Prevention
A Phase 1/2 Multi-Center Trial of Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
What's the purpose of the trial?
Accepting patients
Participating Centers
There are 6 centers participating in this trial. Enter a location below to find the closest center.
Experimental Treatments
Learn more about the experimental treatments being evaluated in this clinical trial.
- Allogeneic Stem Cell Transplant is a type of stem cell transplant that utilizes a donor's pre-collected stem cells to rescue the bone marrow from the toxic effects of very high dose chemotherapy.
- Cyclophosphamide is a chemotherapy agent used in the treatment of cancer.
- Methotrexate is a chemotherapy medication that may be used in the treatment of many different cancers.
- Mycophenolate Mofetil is an immunosuppressive medication used to help prevent rejection in patients who have had a transplant.
- Tacrolimus is an immunosuppressive medication used to help prevent rejection in patients who have had a transplant.
- Vorinostat is an HDAC inhibitor that is FDA approved for use in treating cutaneous T cell lymphoma (CTCL). It is being studied for use in several other indications.
Arms / Cohorts
Explore eligibility, treatments and learn more about potential cohorts.
Accepting patients
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