RPT1G in High Risk MDS

A Phase 1 Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Leukemia Activity of RPT1G in Patients With Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS)

What's the purpose of the trial?

The main goals of this study are to learn if RPT1G is safe and tolerable and to determine the best dose and schedule of RPT1G for patients with relapsed or refractory acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS).
Trial status

Accepting patients

Phase
Phase 1
Enrollment
24
Last Updated

Participating Centers

There are 2 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • RPT1G is a kind of drug called a Nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. RPT1G may work by altering a cancer cells ability to use energy inside the cancer cell.

Arms / Cohorts

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Accepting patients

Cohort 1

Accepting patients

Cohort 2

Accepting patients

Cohort 3

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